It is interesting to notice that in the event the DCM-creating mutation K36Q in cTnI was released in the existence of Ca2+, the simulation confirmed that Ser 22 and 23 not interacted carefully with cTnC, in accord with our speculation the Ca2+-cTnC-cTnI N terminus interaction is unique and is destabilized https://sgc-imllt44320.alltdesign.com/the-smart-trick-of-clazosentan-that-no-one-is-discussing-47905960