These effects, along with a former report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like behavior in mice,two support the thought of concentrating on ACKR3 as a unique approach to modulate the opioid program, which could open up new therapeutic avenues for opioid-connected disorders. At that time, Microsoft https://davidl257olh7.wikinewspaper.com/user