Comment: Barbiturates may maximize adverse effects, which include respiratory despair, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs. pentobarbital will lower the level or influence of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Not known. CYP3A4 inducers https://madonnaf257njc4.worldblogged.com/profile