Not always! Cramping at 10 DPO could be a sign of early pregnancy for some women. It may be relevant to implantation or perhaps the uterus stretching. Even so, it can be a normal premenstrual symptom. The only way to grasp obviously is to wait and take a pregnancy test. https://bookmarkbooth.com/story19564022/the-2-minute-rule-for-depo-10-bonus-20