You will find there's launch of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to reduce afferent suffering transmission and generate analgesia. Thus, medications like clonidine that focus on alpha-two receptors can impact the transmission of ache. Applies to clonidine: oral pill, https://albertk592ccw3.liberty-blog.com/profile