Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of quinine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of exemestane by affecting hepatic/intestinal ... https://bookmarkblast.com/story20363888/poco-conosciuto-fatti-circa-pentobarbital-natrium