Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central nervous system, conolidine modulates alternate molecular targets. A Science Innovations review identified that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By influ... https://elliotjkfvj.frewwebs.com/38201998/new-step-by-step-map-for-conolidin-to-replace-traditional-painkillers